Cone rod dystrophy is characterized by the dysfunction of the cones which, in a high percentage of cases, precedes a degeneration of the rods. Initial signs and symptoms that usually occur in childhood may include decreased sharpness of vision (visual acuity) , abnormal sensitivity to light (photophobia), and loss of central vision. It has a prevalence of between 1: 30,000 and 1: 40,000 individuals. It is inherited following all Mendelian patterns: autosomal dominant, autosomal recessive, and sex-linked. The DBGen Cone and Cane Dystrophy Panel includes the study of the coding regions of 57 genes and 14 deep intronic mutations.