Allows for the simultaneous, automated, fast and accurate sequencing of all the coding regions (exons) of the human genome (approximately 20,000 genes, representing 1% of a human’s DNA) with an average coverage over 90x. These regions contain 85% of the pathogenic mutations described as causing hereditary pathologies in humans. Then, using customized bioinformatics algorithms, genetic variants found in disease causing genes are annotated and analyzed.