Strabismus is a misalignment of the eyes that causes gaze deviation and prevents both eyes from focusing simultaneously. Most cases present a multifactorial inheritance. However, in congenital cranial denervation syndromes, such as Moebius and Duane among others, strabismus is the first identifiable symptom in the first months of life. These syndromes follow a Mendelian inheritance and the causative genes can be identified through genetic tests.

The DBGen Panel of Syndromes that present with Strabismus (Congenital Cranial Dysinnervation Disorders) analyzes the coding regions of 15 genes associated with these pathologies.